SDS Studio™
Toxicology and exposure

LD50 and LC50

InnovaDocs SDS teamUpdated: 6 November 2026

Definition: LD50 is the dose and LC50 the concentration of a substance that kills 50 % of test animals (or aquatic organisms) in a defined test, used to classify acute toxicity.

Oral and dermal LD50 values are in mg/kg body weight; inhalation LC50 in mg/l over 4 hours; aquatic LC50 in mg/l over 96 hours for fish.

They are reported in SDS section 11 (human health) and section 12 (aquatic toxicity) with species, method and source.

Related terms

← All terms

SDS Studio™

Try it free

Create, update or translate one real safety data sheet in SDS Studio™ free of charge. Downloading the finished PDF costs €59 + VAT per SDS, no subscription.

Start your free project →No card needed · 28 languages · EU target-country rules