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Toxicology and exposure

PBT and vPvB

InnovaDocs SDS teamUpdated: 6 November 2026

Definition: PBT means persistent, bioaccumulative and toxic; vPvB means very persistent and very bioaccumulative, assessed with the criteria of REACH Annex XIII.

The result belongs in SDS section 12.5 and, where relevant, section 2.3 and 3. Since Delegated Regulation (EU) 2023/707 PBT/vPvB are also CLP hazard classes with EUH440 and EUH441.

A PBT or vPvB substance requires an SDS even if it is not classified otherwise.

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